Breaking News, Collaborations & Alliances

BMS, Pharmacyclics, Janssen Enter OPDIVO Clinical pact

To evaluate combo drug in hematologic malignancies

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By: Kristin Brooks

Managing Editor, Contract Pharma

Bristol-Myers Squibb, Pharmacyclics, Inc., and Janssen R&D, LLC have entered a clinical trial collaboration to evaluate the safety, tolerability and preliminary efficacy of BMS’ investigational PD-1 immune checkpoint inhibitor OPDIVO (nivolumab) in combination with IMBRUVICA (ibrutinib), an oral Bruton’s tyrosine kinase (BTK) inhibitor co-developed and co-marketed by Pharmacyclics and Janssen. Additional details were not disclosed. Janssen will conduct the Phase 1/2 study evaluating t...

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